Abstract: Objectives There is limited research on the association between sedentary behaviour and breast cancer risk, particularly whether sedentary behaviour is differentially associated with premenopausal and postmenopausal breast cancer. We pooled data from 2 case–control studies from Australia and Canada to investigate this association. Methods This pooled analysis included 1762 incident breast cancer cases and 2532 controls. Participants in both studies completed a lifet

In statistics we have some odd rule of thumbs, despite evidence that does little to support it. All our classic texts say that if we have a sufficient sample size then we can make assumptions about the distribution of the sample mean based on the Central Limit Theorem. In cases that involve the t-distribution, if n ≥ 30 then we can apply the CLT and use the z-value instead of the t-value, and yet the t-value for any given significance level is still pretty far from the respec

Occupational exposure to contaminants is ubiquitous, even if we are not aware of it. Monitoring systems like the US Occupational Safety & Health Administration's Integrated Management Information System is one such system that has provided a wealth of information when it comes to looking at risks of exposures on the job. In 2011 I had the opportunity and privilege to work with Dr. Jérôme Lavoué and Dr. Igor Burstyn to explore what we can do with these monitoring systems with